دانلود کتاب ژنتیک و ژنومیک انسانی Human Genetics and Genomics, Includes Wiley E-Text, 4ed

This fourth edition of the best-selling textbook, Human Genetics and Genomics, clearly explains the key principles needed by medical and health sciences students, from the basis of molecular genetics, to clinical applications used in the treatment of both rare and common conditions.
A newly expanded Part 1, Basic Principles of Human Genetics, focuses on introducing the reader to key concepts such as Mendelian principles, DNA replication and gene expression. Part 2, Genetics and Genomics in Medical Practice, uses case scenarios to help you engage with current genetic practice.
Now featuring full-color diagrams, Human Genetics and Genomics has been rigorously updated to reflect today’s genetics teaching, and includes updated discussion of genetic risk assessment, “single gene” disorders and therapeutics.
Key learning features include:
Clinical snapshots to help relate science to practice
‘Hot topics’ boxes that focus on the latest developments in testing, assessment and treatment
‘Ethical issues’ boxes to prompt further thought and discussion on the implications of genetic developments
‘Sources of information’ boxes to assist with the practicalities of clinical research and information provision
Self-assessment review questions in each chapter
Accompanied by the Wiley E-Text digital edition (included in the price of the book), Human Genetics and Genomics is also fully supported by a suite of online resources at including:
Factsheets on 100 genetic disorders, ideal for study and exam preparation
Interactive Multiple Choice Questions (MCQs) with feedback on all answers
Figures from the book available as PowerPoint slides, ideal for teaching purposes
The perfect companion to the genetics component of both problem-based learning and integrated medical courses, Human Genetics and Genomics presents the ideal balance between the bio-molecular basis of genetics and clinical cases, and provides an invaluable overview for anyone wishing to engage with this fast-moving discipline.
About the Author
Bruce R. Korf is Wayne H. and Sara Crews Finley Chair in Medical Genetics, Professor and Chair, Department of Genetics, and Director, Heflin Center for Genomic Sciences, at the University of Alabama at Birmingham
Mira B. Irons is Park Gerald Chair in Genetics and Associate Chief, Division of Genetics, at the Children’s Hospital Boston, and Associate Professor of Pediatrics at Harvard Medical School
Contents
CHAPTER 1: DNA Structure and Function
CHAPTER 2: Genetic Variation
CHAPTER 3: Patterns of Inheritance
CHAPTER 4: The Human Genome
CHAPTER 5: Multifactorial Inheritance
CHAPTER 5: Cell Division and Chromosomes
CHAPTER 7: Population Genetics
CHAPTER 8: Cancer Genetics
CHAPTER 9: Chromosome Translocation
CHAPTER 10: Molecular Diagnosis
CHAPTER 11: Newborn Screening
CHAPTER 12: Developmental Genetics
CHAPTER 13: Carrier Screening
CHAPTER 14: Genetic Risk Assessment
CHAPTER 15: Genetic Testing for Risk of Cancer
CHAPTER 16: Pharmacogenetics
CHAPTER 17: Treatment of Genetic Disorders