دانلود کتاب پزشکی دقیق بالینی: یک شروع Clinical Precision Medicine: A Primer, 1ed

Clinical Precision Medicine: A Primer offers clinicians, researchers and students a practical, up-to-date resource on precision medicine, its evolving technologies, and pathways towards clinical implementation. Early chapters address the fundamentals of molecular biology and gene regulation as they relate to precision medicine, as well as the foundations of heredity and epigenetics. Oncology, an early adopter of precision approaches, is considered with its relationship to genetic variation in drug metabolism, along with tumor immunology and the impact of DNA variation in clinical care.
Contributions by Stephanie Kramer, a Clinical Genetic Counselor, also provide current information on prenatal diagnostics and adult genetics that highlight the critical role of genetic counselors in the era of precision medicine.
Includes applied discussions of chromosomes and chromosomal abnormalities, molecular genetics, epigenetic regulation, heredity, clinical genetics, pharmacogenomics and immunogenomics
Features chapter contributions from leaders in the field
Consolidates fundamental concepts and current practices of precision medicine in one convenient resource
Review
“This is an excellent consultative resource that is brief and specific. It will be instrumental to readers looking for easy-to-read basic information on the current knowledge in precision medicine applied to human genetics. Dr. Crabtree has done an excellent job in editing this book. Congratulations on a great contribution.” –Doody
Review
A practical, up-to-date resource for clinicians, researchers and students interested in precision medicine, evolving technologies, and pathways towards clinical implementation
Contents
Chapter 1. Cytogenetics in precision medicine
Chapter 2. Molecular genetics—the basics of gene expression
Chapter 3. Fundamentals of epigenetics
Chapter 4. Fundamentals of heredity
Chapter 5. Clinical genetics
Chapter 6. Pharmacogenomics
Chapter 7. Immunogenomics: steps toward personalized medicines
Chapter 8. Technology of clinical genomic testing