دانلود کتاب اهداف درمانی برای تغییر کاربرد دارو در استئوآرتریت Therapeutic Targets for Drug Repurposing in Osteoarthritis

Therapeutic Targets for Drug Repurposing in Osteoarthritis book aims to serve as a vital resource in the quest to develop more effective treatments for osteoarthritis. Leveraging recent advancements in molecular biology, it lists and explains the roles of various pro-inflammatory molecules, enzymes, growth factors, and signaling pathways implicated in the disease. This includes detailed discussions on cytokines known to drive inflammation and joint degradation in osteoarthritis. This book also covers enzymes that play critical roles in cartilage breakdown and joint damage progression. Additionally, it explores the Wnt/β-catenin signaling pathway and its regulatory molecules, highlighting their dual roles in cartilage homeostasis and inflammation. Growth factors are examined for their potential to promote tissue repair and modulate inflammatory responses.
Contents
۱ An Overview of Osteoarthritis
۲ Key Interleukins and Enzymes
۳ Targeting Receptors
۴ Targeting Crosstalking Pathways – Growth Factors and Signaling Networks
۵ RNA-Based Therapeutic Targets